Mikro Biyosistemler


Using its microfluidics know-how, Mikro Biyosistemler has developed the following lab-on-a-chip applications:

  1. tagCTC, a Circulating Tumor Cell (CTC) detection system for diagnosis and prognosis of cancer
  2. tagCTC is a sample-in/answer-out blood test that isolates high purity and live CTCs from the blood samples of cancer patients and instantly counts the isolated cells.
  3. Microfluidics consultancy and fabrication services for companies and institutions.
  4. Mikro Biyosistemler has experience with particle manipulation and sorting, specifically animal cells, based on their physical (size, deformability), biochemical (surface proteins), and electrical properties (electrical conductivity and impedance).

Partnering Objectives

Mikro Biyosistemler is interested in:

1- Partnering with entities that can collaborate on product development and manufacturing, including but not limited to:

  • Polymer manufacturers that also have expertise on chemical surface coating technologies and microfluidics.
  • Automation companies for developing our production tools and analyzer devices
  • Biotech companies – antibody manufacturers

2- Joint R&D and joint product development with:

  1. Biopharmaceutical companies, oncology centres or universities looking for expertise in MEMS/microfluidic design, fabrication, or testing:
  • To validate the results obtained with our device
  • To analyse new biomarkers using CTCs
  • To develop new applications in precision medicine for cancer
  • To explore new business opportunities

3- Finding leading cancer centres or academic institutions to conduct clinical studies to:

  • Provide clinical data to support out-licensing of innovations
  • To investigate the use of our system as a diagnostic tool for different types of solid tumors.

4- Providing consultancy services to UK entitites developing new innovations of use to Turkey and other countries:

  • Entities may benefit from our products as an upstream process for their processes

5- Meeting to discuss regulatory and reimbursement strategies; e.g. with:

  • IVD Regulatory Consulting companies: Certification will be much easier if we can partner with a UK consultancy firm. Even most of the trainings on the regulatory requirements for IVDs are held in UK.
  • IVD Reimbursement Consulting companies

Company Story

Mikro Biyosistemler is a seed-funded spin-off from Orta Doğu Teknik Üniversitesi (ODTÜ) MEMS Center founded in 2015, and develops microfluidic systems for cancer diagnostics. Our core product, tagCTC, is a liquid biopsy test for cancer patients, which detects Circulating Tumor Cells (CTC) from blood samples. Our product is positioned as an alternative to conventional tissue biopsies, which provide limited information about tumor heterogeneity and are painful, costly, and even impossible to perform for specific cancer types. tagCTC stands out among its competitors thanks to its unique microfluidic technology, that enables very high purity and live CTC isolation with an instant count information of the collected cells. With this, we aim to respond to the needs of both the patients and the hospitals/cancer centers.

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